Prolongation of the QT Interval Observed in a Japanese Patient with Vivax Malaria Following Treatment with Halofantrine
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QT interval prolongation in a patient with LQT2 on levetiracetam
We report the case of a 24-year old female with a seizure disorder and previously undiagnosed long QT syndrome whose QT interval increased and developed into torsades de pointes after her levetiracetam dose was increased. The patient had been having seizures since age 10. The episodes typically occurred in the early morning and witnesses describe shaking of her entire body, incontinence, and wh...
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In 1991, some 90 countries or areas where 42% of the world's population resided were considered malarious and estimation of malaria mortality worldwide per year was 1.5 to 3 million'). The Ministry of Justice reported that the total number of Japanese who went abroad was as many as 11,790, 699 and the number of foreigners who entered Japan for the first time was 3,251,753 in 1992. Consequently ...
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INTRODUCTION The QT interval prolongation is an adverse effect associated with moxifloxacin. This adverse effect can lead to potentially life-threatening arrhythmias such as Torsades de pointes. We describe a case of severe QT interval prolongation associated with moxifloxacin which may cause the development of Torsades de pointes. There have been no reported case of severe corrected QT interva...
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N Engl J Med 2004;350:1013-22. Copyright © 2004 Massachusetts Medical Society. n the past decade, the single most common cause of the withdrawal or restriction of the use of drugs that have already been marketed has been the prolongation of the QT interval associated with polymorphic ventricular tachycardia, or torsade de pointes (Fig. 1), which can be fatal. 1 Nine structurally unrelated drugs...
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In hypertensive patients single doses of ketanserin 40 mg prolonged the corrected QT interval (QTc) for at least 8 hours, with a maximal increase of 35 ms (P less than 0.001, n = 6) after 2 hours. During chronic dosing (20 and 40 mg b.d.) the QTc was further prolonged, by 46 and 45 ms respectively. QTc prolongation after treatment with a mean dose of 73 mg/day for 7 weeks (n = 26) was significa...
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ژورنال
عنوان ژورنال: Journal of the Japanese Association for Infectious Diseases
سال: 1995
ISSN: 1884-569X,0387-5911
DOI: 10.11150/kansenshogakuzasshi1970.69.1408